|
Tadaflo 5 mg (Tadalafil) is contraindicated with medications containing nitrates due to the potential for severe hypotension (dangerously low blood pressure) that can occur when both drugs are used together. Here's why: Mechanism of Action: Tadalafil, the active ingredient in Tadaflo, is a phosphodiesterase type 5 (PDE5) inhibitor. It works by increasing blood flow to the penis during sexual stimulation, thus aiding in achieving and maintaining an erection. Nitrates: Medications containing nitrates (such as nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate) are primarily used to treat angina (chest pain) and heart conditions. Nitrates work by dilating blood vessels to increase blood flow to the heart and reduce its workload. Dangerous Interaction: Both Tadaflo 5 mg and nitrates cause vasodilation (widening of blood vessels), which can lead to a significant drop in blood pressure when used together. This drop in blood pressure can be severe and potentially life-threatening. Contraindication: Due to the risk of hypotension, the concomitant use of Tadalafil with nitrates is contraindicated. This means it is strongly advised against and should be avoided completely. Patients prescribed Tadaflo should inform their healthcare provider about all medications they are taking, especially nitrates or any medications used for heart conditions. Patient Safety: Healthcare providers need to carefully assess a patient's medical history and current medications before prescribing Tadalafil to ensure there are no contraindications. Patients should also be educated about the risks of combining Tadaflo with nitrates and instructed to seek immediate medical attention if they experience symptoms such as dizziness, lightheadedness, fainting, or chest pain while taking both medications.
In summary, the contraindication of Tadaflo 5 mg with nitrates is due to the potential for severe hypotension resulting from the combined vasodilatory effects of both medications.
|
Reagovat
11.04.2022